What is Crohn's disease ?
Crohn's disease, also known as Crohn syndrome and regional enteritis, is an inflammatory bowel disease (IBD) It causes inflammation of the lining of your digestive tract and may affect any part of the gastrointestinal tract which can lead to abdominal pain, severe diarrhea, fatigue, weight loss and malnutrition. Inflammation caused by this disease can involve different areas of the digestive tract in different people. The inflammation it causes often spreads deep into the layers of affected bowel tissue. Crohn's disease can be both painful and debilitating, and sometimes may lead to life-threatening complications, More than a half a million American men and women have been diagnosed with Crohn’s, Inflammation is at the root of their symptoms, Crohn's disease can lead to several mechanical complications within the intestines, including obstruction, fistulae, and abscesses.
Obstruction typically occurs from strictures or adhesion's that narrow the lumen blocking the passage of the intestinal contents, Fistulae can develop between two loops of bowel, between the bowel and bladder, between the bowel and vagina, and between the bowel and skin, Abscesses are walled off collections of infection which can occur in the abdomen or in the perianal area, Crohn's is responsible for 10% of vesicoenteric fistulae and is the most common cause of ileovesical fistulae.
Crohn's disease also increases the risk of cancer in the area of inflammation for example, individuals with Crohn's disease involving the small bowel are at higher risk for small intestinal cancer, Similarly, people with Crohn's colitis have a relative risk of 5.6 for developing colon cancer, Screening for colon cancer with colonoscopy is recommended for anyone who has had Crohn's colitis for at least eight years, Some studies suggest there is a role for chemoprotection in the prevention of colorectal cancer in Crohn's involving the colon; two agents have been suggested, folate and mesalamine preparations. Individuals with Crohn's disease are at risk of malnutrition for many reasons including decreased food intake and malabsorption, The risk increases following resection of the small bowel such individuals may require oral supplements to increase their caloric intake or in severe cases total parenteral nutrition (TPN) Most people with moderate or severe Crohn's disease are referred to a dietitian for assistance in nutrition,The major significant complications of Crohn's disease including bowel obstruction, abscesses, free perforation and hemorrhage (in rare cases) may be fatal,
Crohn's disease can be problematic during pregnancy and some medications can cause adverse outcomes for the fetus or mother, Consultation with an obstetrician and gastroenterologist about Crohn's disease and all medications facilitates preventative measures, In some cases remission occurs during pregnancy and Certain medications can also lower sperm count or otherwise adversely affect a man's fertility.
Crohn's disease, also known as Crohn syndrome and regional enteritis, is an inflammatory bowel disease (IBD) It causes inflammation of the lining of your digestive tract and may affect any part of the gastrointestinal tract which can lead to abdominal pain, severe diarrhea, fatigue, weight loss and malnutrition. Inflammation caused by this disease can involve different areas of the digestive tract in different people. The inflammation it causes often spreads deep into the layers of affected bowel tissue. Crohn's disease can be both painful and debilitating, and sometimes may lead to life-threatening complications, More than a half a million American men and women have been diagnosed with Crohn’s, Inflammation is at the root of their symptoms, Crohn's disease can lead to several mechanical complications within the intestines, including obstruction, fistulae, and abscesses.
Obstruction typically occurs from strictures or adhesion's that narrow the lumen blocking the passage of the intestinal contents, Fistulae can develop between two loops of bowel, between the bowel and bladder, between the bowel and vagina, and between the bowel and skin, Abscesses are walled off collections of infection which can occur in the abdomen or in the perianal area, Crohn's is responsible for 10% of vesicoenteric fistulae and is the most common cause of ileovesical fistulae.
Crohn's disease also increases the risk of cancer in the area of inflammation for example, individuals with Crohn's disease involving the small bowel are at higher risk for small intestinal cancer, Similarly, people with Crohn's colitis have a relative risk of 5.6 for developing colon cancer, Screening for colon cancer with colonoscopy is recommended for anyone who has had Crohn's colitis for at least eight years, Some studies suggest there is a role for chemoprotection in the prevention of colorectal cancer in Crohn's involving the colon; two agents have been suggested, folate and mesalamine preparations. Individuals with Crohn's disease are at risk of malnutrition for many reasons including decreased food intake and malabsorption, The risk increases following resection of the small bowel such individuals may require oral supplements to increase their caloric intake or in severe cases total parenteral nutrition (TPN) Most people with moderate or severe Crohn's disease are referred to a dietitian for assistance in nutrition,The major significant complications of Crohn's disease including bowel obstruction, abscesses, free perforation and hemorrhage (in rare cases) may be fatal,
Crohn's disease can be problematic during pregnancy and some medications can cause adverse outcomes for the fetus or mother, Consultation with an obstetrician and gastroenterologist about Crohn's disease and all medications facilitates preventative measures, In some cases remission occurs during pregnancy and Certain medications can also lower sperm count or otherwise adversely affect a man's fertility.
